Convert VitaFOXO VITAFOXO to DIMO DIMO

This project will design a new RNA therapeutic that nudges the longevity-linked FOXO3 gene into its health-promoting form to halt the tissue breakdown behind degenerative disc disease—opening a precise, scalable route to drugs that extend healthspan. Dr. Lorna Harries’ lab has identified an innovative way to modulate FOXO3, a well known and yet undrugged longevity target, and propose leveraging it to address chronic lower back pain stemming from degenerative disc disease. They plan to make short, lab-made modified RNA molecules (antisense oligonucleotides) that selectively switch FOXO3’s “good” message on, first in human cells and mini-disc models. Success would yield 1) a lead drug candidate, 2) proof it can restore disc health, and 3) the data needed for patenting and further development. The same molecules could later be adapted to treat many other age-related conditions, helping people stay healthy for longer.

DIMO is the utility token powering the future machine economy. Starting with connected vehicles, the DIMO protocol creates blockchain-based identities for cars, drivers, apps, and sensors, enabling them to interact, transact, and coordinate autonomously. Vehicle owners earn DIMO tokens by sharing their data, while the token also governs this emerging protocol for machine-to-machine interactions. Built with open-source components on the Ethereum Virtual Machine, DIMO aims to increase transparency, privacy, and reliability in IoT networks, thereby fostering trust among users and developers. DIMO can expand beyond cars to robotics, energy, and other IoT categories in the future.